VNEW®

Decellularized Dermal Allografts

Reshaping Female Pelvic Health

VNEW® -
The Future of the Pelvic Floor Takes Shape

VNEW® Precut Shaped Decellularized Dermal Allografts are designed to support surgical procedures by reinforcing, repairing, or replacing damaged or inadequate integumental tissue, providing a versatile solution for homologous uses of human integument.

Benefits of VNEW®

Precision and Efficiency

VNEW comes in two pre-cut shapes for anterior and posterior use, reducing surgery time by eliminating in-surgery adjustments.

Advanced Healing

Using dCELL® Technology, VNEW supports cell integration and natural tissue remodeling while minimizing the risk of immune rejection.

Versatility

Designed for pelvic floor conditions and gender affirmation surgeries, VNEW adapts to various surgical approaches, enhancing patient care.

Pioneering Synthetic-free Solutions for Women’s Pelvic Health

Cystocele is a medical term that describes a condition where the bladder bulges into the front wall of the vagina. This happens when the muscles and tissues that support the bladder become weak or damaged. It can occur after childbirth or due to heavy lifting, obesity, or aging. When a cystocele happens, a person might feel pressure or discomfort in the pelvic area, have trouble emptying the bladder completely, or notice a bulge in the vagina. It’s important to talk to a doctor if someone has these symptoms, as there are treatments available to help.

Rectocele is a medical term that describes a condition where the rectum (the part of the intestines that stores stool) bulges into the back wall of the vagina. This happens when the muscles and tissues that support the rectum become weak or damaged, often due to childbirth, aging, or heavy lifting.

When someone has a rectocele, they might feel pressure or discomfort in the pelvic area. They may also have trouble with bowel movements or notice a bulge in the vagina. It’s important to talk to a doctor if these symptoms occur because there are treatments available to help.

Synthetic Mesh Removal is a surgery to take out mesh implants used to support organs like the bladder or rectum. Some people may need this procedure if they have problems like pain or infection from the mesh.

Doctors usually perform the removal by making an incision to access the mesh and carefully taking it out. They can use traditional surgery or minimally invasive techniques, depending on the situation.

Enterocele is like a vaginal hernia. It happens when a part of the small intestine pushes into the space between the vagina and the rectum, creating a bulge. This occurs when the muscles and tissues that normally support these organs become weak or damaged, often due to childbirth, aging, or heavy lifting.

Just like a hernia in other parts of the body, an enterocele can cause discomfort, pressure in the pelvic area, or a noticeable bulge. If someone experiences these symptoms, it’s important to talk to a doctor because there are treatments available to help.

Apical Prolapse is a condition where the top part of the vagina (the apex) drops down because the supporting tissues and muscles have become weak or damaged. This can happen after childbirth, during menopause, or due to heavy lifting.

When someone has apical prolapse, they may feel pressure or discomfort in the pelvic area, have trouble with bladder or bowel control, or notice a bulge in the vagina. It’s important to talk to a doctor if these symptoms occur, as there are treatments available to help.

A fistula is a small tunnel that forms between two parts of the body that shouldn’t be connected, like between the bladder (which holds urine) and the vagina, or between the intestines (which carry stool) and the skin. This can happen due to injury, infection, or surgery.

If someone has a fistula, they might notice urine or stool leaking where it shouldn’t, or they may feel pain. It’s important to see a doctor if this happens, as there are treatments to help fix it.

Rectal Prolapse occurs when the rectum (the part of the intestines where stool exits the body) slips out of its normal position and protrudes through the anus. This can happen when the muscles and tissues that support the rectum become weak, often due to factors like aging, chronic constipation, or straining during bowel movements.

How It Differs from Hemorrhoids: Unlike hemorrhoids, which are swollen blood vessels in the rectal area that can cause pain and bleeding, rectal prolapse involves the entire rectum coming out of the body. While both can cause discomfort and may appear similar, rectal prolapse is a more serious condition that may require surgery.

If someone has rectal prolapse, they might notice a bulge or swelling, especially during bowel movements. They may also experience discomfort, bleeding, or a feeling that something is not right. It’s important to see a doctor if these symptoms occur, as there are treatments available to help.

Stress Urinary Incontinence (SUI) is a condition where a person leaks urine during activities that put pressure on the bladder, such as laughing, coughing, sneezing, or exercising. This happens when the muscles that control the bladder become weak or when the pelvic floor support is compromised, often due to factors like pregnancy, childbirth, aging, or obesity.

People with SUI may feel embarrassed or frustrated by these unexpected leaks. It’s important to talk to a doctor if these symptoms occur, as there are effective treatments available, including lifestyle changes, pelvic floor exercises, and surgical options.

Complex Gender Procedures involve various surgeries that assist individuals in transitioning to their identified gender. These may include surgeries such as breast augmentation, genital reconstruction, and facial feminization or masculinization.

Using Acellular Dermis (like VNEW): Acellular dermis is a type of tissue that can be used in surgeries to provide structural support. In gender-affirming surgeries, VNEW might be utilized as a graft in procedures like vaginal or penile reconstruction. Its properties may contribute to the surgical process and patient outcomes.
Overall, acellular dermis like VNEW can be an option considered in complex gender procedures, and its use can vary based on the specific needs of the patient and the surgical approach.

During Cervical cancer treatment, patients may experience changes in vaginal length and narrowing. Surgical procedures like hysterectomy can lead to a shorter vaginal canal and affect elasticity, while radiation therapy may cause scarring and tightness, resulting in a narrower vaginal opening. These changes can lead to discomfort and difficulties during intercourse.

VNEW, an acellular dermis product, may be used in surgical reconstruction to help address these issues by providing structural support and promoting healing. This could aid in restoring vaginal length and elasticity, improving comfort and sexual function for patients.

Pioneering Synthetic-free Solutions
for Women’s Pelvic Health

Cystocele is a medical term that describes a condition where the bladder bulges into the front wall of the vagina. This happens when the muscles and tissues that support the bladder become weak or damaged. It can occur after childbirth or due to heavy lifting, obesity, or aging. When a cystocele happens, a person might feel pressure or discomfort in the pelvic area, have trouble emptying the bladder completely, or notice a bulge in the vagina. It’s important to talk to a doctor if someone has these symptoms, as there are treatments available to help.

Rectocele is a medical term that describes a condition where the rectum (the part of the intestines that stores stool) bulges into the back wall of the vagina. This happens when the muscles and tissues that support the rectum become weak or damaged, often due to childbirth, aging, or heavy lifting.

When someone has a rectocele, they might feel pressure or discomfort in the pelvic area. They may also have trouble with bowel movements or notice a bulge in the vagina. It’s important to talk to a doctor if these symptoms occur because there are treatments available to help.

Synthetic Mesh Removal is a surgery to take out mesh implants used to support organs like the bladder or rectum. Some people may need this procedure if they have problems like pain or infection from the mesh.

Doctors usually perform the removal by making an incision to access the mesh and carefully taking it out. They can use traditional surgery or minimally invasive techniques, depending on the situation.

Enterocele is like a vaginal hernia. It happens when a part of the small intestine pushes into the space between the vagina and the rectum, creating a bulge. This occurs when the muscles and tissues that normally support these organs become weak or damaged, often due to childbirth, aging, or heavy lifting.

Just like a hernia in other parts of the body, an enterocele can cause discomfort, pressure in the pelvic area, or a noticeable bulge. If someone experiences these symptoms, it’s important to talk to a doctor because there are treatments available to help.

Apical Prolapse is a condition where the top part of the vagina (the apex) drops down because the supporting tissues and muscles have become weak or damaged. This can happen after childbirth, during menopause, or due to heavy lifting.

When someone has apical prolapse, they may feel pressure or discomfort in the pelvic area, have trouble with bladder or bowel control, or notice a bulge in the vagina. It’s important to talk to a doctor if these symptoms occur, as there are treatments available to help.

A fistula is a small tunnel that forms between two parts of the body that shouldn’t be connected, like between the bladder (which holds urine) and the vagina, or between the intestines (which carry stool) and the skin. This can happen due to injury, infection, or surgery.

If someone has a fistula, they might notice urine or stool leaking where it shouldn’t, or they may feel pain. It’s important to see a doctor if this happens, as there are treatments to help fix it.

Rectal Prolapse occurs when the rectum (the part of the intestines where stool exits the body) slips out of its normal position and protrudes through the anus. This can happen when the muscles and tissues that support the rectum become weak, often due to factors like aging, chronic constipation, or straining during bowel movements.

How It Differs from Hemorrhoids: Unlike hemorrhoids, which are swollen blood vessels in the rectal area that can cause pain and bleeding, rectal prolapse involves the entire rectum coming out of the body. While both can cause discomfort and may appear similar, rectal prolapse is a more serious condition that may require surgery.

If someone has rectal prolapse, they might notice a bulge or swelling, especially during bowel movements. They may also experience discomfort, bleeding, or a feeling that something is not right. It’s important to see a doctor if these symptoms occur, as there are treatments available to help.

Stress Urinary Incontinence (SUI) is a condition where a person leaks urine during activities that put pressure on the bladder, such as laughing, coughing, sneezing, or exercising. This happens when the muscles that control the bladder become weak or when the pelvic floor support is compromised, often due to factors like pregnancy, childbirth, aging, or obesity.

People with SUI may feel embarrassed or frustrated by these unexpected leaks. It’s important to talk to a doctor if these symptoms occur, as there are effective treatments available, including lifestyle changes, pelvic floor exercises, and surgical options.

Complex Gender Procedures involve various surgeries that assist individuals in transitioning to their identified gender. These may include surgeries such as breast augmentation, genital reconstruction, and facial feminization or masculinization.

Using Acellular Dermis (like VNEW): Acellular dermis is a type of tissue that can be used in surgeries to provide structural support. In gender-affirming surgeries, VNEW might be utilized as a graft in procedures like vaginal or penile reconstruction. Its properties may contribute to the surgical process and patient outcomes.
Overall, acellular dermis like VNEW can be an option considered in complex gender procedures, and its use can vary based on the specific needs of the patient and the surgical approach.

During Cervical cancer treatment, patients may experience changes in vaginal length and narrowing. Surgical procedures like hysterectomy can lead to a shorter vaginal canal and affect elasticity, while radiation therapy may cause scarring and tightness, resulting in a narrower vaginal opening. These changes can lead to discomfort and difficulties during intercourse.

VNEW, an acellular dermis product, may be used in surgical reconstruction to help address these issues by providing structural support and promoting healing. This could aid in restoring vaginal length and elasticity, improving comfort and sexual function for patients.

Advancing the Science with dCELL® Technology.

Study demonstrating the benefits of VNEW over Native Tissue

Study Design:

Study Outcomes:

FAQ

What is Cystocele?

Cystocele is the most common type of a pelvic organ prolapse. Otherwise known as a prolapsed bladder, a cystocele tends to occur when the bladder pushes into the vaginal cavity. 

What are Symptoms of Cystocele?

Symptoms of cystocele include, but are not limited to:

  • Consistent vaginal pressure
  • Urinary incontinence
  • An inability to properly and fully empty one’s bladder
What are the Options for Cystocele Repair?

 When it comes to cystocele repair, there are four primary types of surgical options:

  • Anterior colporrhaphy
  • Anterior colporrhaphy with graft
  • Paravaginal repair 
  • Sacral colpopexy
    • On the majority, anterior colporrhaphy and anterior colporrhaphy with graft are the most common.
What is an Apical Prolapse?

Apical prolapse, otherwise known as uterine prolapse, is a condition wherein the uterus drops down into the vagina. It typically occurs as a result of a (1) hysterectomy, or (2) weakened pelvic floor muscles as a result of childbirth, ageing, or other variables affecting the strength of one’s pelvic floor.

What is Rectal Prolapse?

Rectal prolapse is a condition wherein the rectum drops, or falls out of, the anus. Although rectal prolapse can lead to discomfort and slight pain, it rarely is a medical emergency.

What Causes Rectal Prolapse?

There can be many diverse and varied causes to rectal prolapse. However, some of the most common include:

  • Consistent constipation and irregular bowel movements
  • Childbirth
  • Ageing
  • Chronic pelvic pain and injury
Can Rectal Prolapse Heal Itself?

In adults, although rectal prolapse is not an immediate medical injury, it more often than not does not heal itself. In order to correct or fix rectal prolapse, surgery is typically the primary solution.

What are Some of the Most Common Rectal Prolapse Treatments?

First, before deciding upon a treatment for rectal prolapse, visit your primary care physician to ensure that rectal prolapse has occurred. After receiving a proper diagnosis, note that there are many rectal prolapse treatments available, both invasive and non-invasive.

  • Non-invasive treatments:
    • If your primary care physician has noted that your rectal prolapse is not severe and caused by dietary habits, consider increasing your fiber intake as well as your exercise.
  • Invasive and Surgical treatments:
    • If your primary care physician has deemed your rectal prolapse as needing surgery, there are three primary solutions:
      • Rectopexy: This procedure involves connecting the rectum to the back of the pelvis
      • Perineal procedures: As the perineum is the area directly around the circumference of the anus, these types of procedures typically involve attaching the rectum to the large intestine, or, for mucosal-specific prolapses, removing the lining of the rectum entirely, then folding it back over the muscular layer. 
      • Anterior Resection: The above treatments involve reconnecting or attaching the rectum or surrounding areas to another body part. An anterior resection, however, differs in that it removes a segment of the rectum and colon entirely.
Rectal Prolapse vs. Hemorrhoids: What’s the Difference?

This is a common question, and should be considered with care. The primary difference between a rectal prolapse and hemorrhoids is that a rectal prolapse involves the anus actually falling or dropping, while haemorrhoids are simply swollen veins that protrude in the anus. As the symptoms of each are similar, please consult a primary care physician before making an assumption. 

What is a Rectocele?

A rectocele involves the rectum pushing into or pressing against the vagina as a result of weakened pelvic floor muscles. 

What are Symptoms of Rectocele?

Symptoms of rectocele involve, but are not limited to:

  • The physical feeling of tension (i.e. a “bulge”) against the vagina
  • Consistent rectal tension, tightness, or pressure
  • The feeling that something will seemingly “fall out” of the rectum/pelvis.
  • Constipation and lack of bowel movement
When is Rectocele Surgery Needed?

Rectocele surgery should be considered only when non-invasive treatments and solutions fail. Specifically, before considering surgery, consider plausible solutions such as:

  • Pelvic strengthening exercises
  • Dietary and lifestyle changes
  • Bowel training
    • If these exercises are not enough, and your rectocele issues are combined with any forms of pelvic organ prolapse, consider surgery with your primary care physician.
What are the Most Common Ways to Repair a Rectocele?

The most common surgical solutions for a repaired rectocele involves four primary options:

  • Posterior colporrhaphy
  • Posterior vaginal repair
    • Abdominal rectopexy
      • For less serious cases, meanwhile, consider a vaginal pessary.
What is a Fistula?

A fistula is a connection between two organs. Typically, this connection appears to be tube-like, and is often visualized as a “bridge” between such organs that should not be there in the first place.

What is an Anal Fistula?

An anal fistula is an infectious opening that occurs between the inside of the anus and the surrounding skin. Typically an abscess forms, thereby causing inflammation and liquid to form. 

What Causes Anal Fistula?

Anal fistulas are the primary result of an anal gland infection. Although anal gland infections are typically not a cause for concern of something greater, consult with your primary care physician. In more extreme or rare cases, anal fistulas can be caused by:

  • Crohn’s 
  • Tuberculosis
  • HIV
What is Stress Urinary Incontinence (SUI)?

Stress urinary incontinence, otherwise known as SUI, is a condition that involves the excess leaking of urine during physical exercise, as well as other abdominally straining-intensive actions such as sneezing or coughing. It is typically caused, meanwhile, by weakened muscles surrounding both the bladder and urethra. 

What are the Best Ways to Treat Stress Urinary Incontinence (SUI)?

Before considering invasive options, there are many ways to improve SUI if its symptoms are not debilitating or serious. Specifically, consider pelvic floor exercises,  lifestyle changes such as increased exercise with balanced rest, and even certain FDA-approved medications.

If your stress urinary incontinence is more serious, there are many surgical solutions, including but not limited to urethral slings and artificial urinary sphincters.

What are the Symptoms and Signs of Cervical Cancer?

First and foremost, consistent preventative check-ups and annual appointments are crucial towards detecting early-stage cervical cancer, as its early stages do not have many warming signs. In later-stage cervical cancer, however, symptoms can include:

  • Vaginal bleeding
  • Pain and discomfort during sex
  • Irregular vaginal discharge
What are Some Common Treatments for Cervical Cancer?

There are many common treatments for cervical cancer. Some of them include:

  • Surgeries to remove parts of the uterus, lymph nodes, or cervix.
  • Radiation 
  • Chemotherapy
    • If caught early enough, a hysterectomy or trachelectomy are the primary surgical options
Is Cervical Cancer Genetic?

Not directly. Genetic predispositions to HPV, as well as external environmental factors, can certainly increase the chances of cervical cancer. However, the actual cancer itself is not genetic.

Reshaping Female Pelvic Health