dCELL Technology®
Decellularized Dermal Allografts For Urinary, Reproductive, & Digestive Health
What is dCELL® Technology?
dCell® Technology employs a gentle soft tissue decellularization process that removes over 99% of DNA and cellular material, significantly reducing the risk of rejection while preserving the tissue structure.
This technology maintains the natural acellular scaffold of the tissue, facilitating cellular proliferation, angiogenesis, reduced fibrosis, and structural support, making it ideal for pelvic floor procedures.
dCell® Technology’s processing ensures the retention of strong biomechanical properties, offering a profile specifically designed for women’s health and ensuring high suture pull-out strength. This makes the tissue suitable for various surgical techniques, including trans-vaginal, laparoscopic, and robot-assisted surgeries, catering to diverse surgical preferences and requirements.
Benefits of dCELL® Technology
Lower Immunogenocity
lower immunogenicity due to decellularized donor tissue with nearly no structural disruption and near complete removal of donor cells and 99% of donor DNA.
No Structural Destruction
The result is lower immunogenicity due to decellularized donor tissue with nearly no structural disruption
Built for Stability
The dCELL® process delivers the long-term strength needed to maintain structural integrity, supporting the development of permanent vasculature and cellular integration, unlike competitive technologies that may degrade prematurely.
How does dCELL® Technology Work?
What is an Intact Extracellular Matrix?
Tissue with dCELL® Technology has an intact extracellular matrix and vascular-like channels needed for revascularization.
An intact extracellular matrix (ECM) is a complete network of molecules that provides structural and biochemical support to cells, ensuring tissue integrity and optimal function.
Key components include:
- Binding cells to ECM and surrounding tissue
- Tensile strength
- Structural support
- Cell migration matrix creation for signaling and adhesion.
But all decellularization and tissue processing are the same…
Among the human acellular dermis products being used in pelvic floor surgery, there are major differences in decellularization processes.
The Difference is dCELL®
DermaPure® and VNEW® set themself apart from other tissue options and decellularization processes by using the unique and patented dCELL® Technology. The result is lower immunogenicity because the decellularized donor tissue has nearly no structural disruption, with over 99% of the donor DNA removed.
What is an Intact Extracellular Matrix?
An intact extracellular matrix (ECM) is a complete network of molecules that provides structural and biochemical support to cells, ensuring tissue integrity and optimal function.
Key components include:
- Binding cells to ECM and surrounding tissue
- Tensile strength
- Structural support
- Cell migration matrix creation for signaling and adhesion.
But all decellularization and tissue processing are the same…
Among the human acellular dermis products being used in pelvic floor surgery, there are major differences in decellularization processes.
